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Properties of substance:
cis-diamminedichloroplatinum
Synonyms:
cisplatin
Group of substances:
inorganic
Physical appearance:
crystals
Empirical formula (Hill's system for organic substances):
H
6
Cl
2
N
2
Pt
Structural formula as text:
[Pt(NH3)2Cl2]
Molar/atomic mass: 300.045
Decomposition temperature (°C):
270-275
CAS №: 15663-27-1
Solubility (g/100 g of solvent):
dimethylformamide
: soluble [
Ref.
]
water
: 0.253 (25°C) [
Ref.
]
LD
50
(mg/kg):
3.4 (rats, intravenous)
9.7 (guinea pig, intravenous)
Uses:
drug: antineoplastic [
Ref.
]
References:
Kleemann A. Pharmaceutical Substances. - 2000. - pp. 487-488
Lewis R.J. Sax's Dangerous Properties of Industrial Materials. - 12ed., Vol. 1-5. - Wiley, 2012. - pp. 3672-3673
The Merck Index. - 15th ed. - Royal Society of Chemistry, 2013. - pp. 414
Лидин Р.А., Андреева Л.Л., Молочко В.А. Константы неорганических веществ. - М.: Дрофа, 2006. - pp. 157 [Russian]
Некрасов Б.В. Основы общей химии. - Т.2. - М.: Химия, 1973. - pp. 455 [Russian]
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© Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru