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Properties of substance:

isoniazid



skc-file

Physical appearance:

white crystals

Empirical formula (Hill's system for organic substances):

C6H7N3O

CAS No: 54-85-3

Molar/atomic mass: 137.139

Melting point (°C):

172

Solubility (g/100 g of solvent):

water: 10.71 (20°C) [Ref.]
water: 12.28 (25°C) [Ref.]
water: 20.63 (40°C) [Ref.]
diethyl ether: practically insoluble [Ref.]
chloroform: difficulty soluble [Ref.]
ethanol: difficulty soluble [Ref.]

    LD50 (mg/kg):

    1400 (, oral)
    150 (white mice, oral)
    1250 (rats, oral)
    365 (rats, intravenous)
    133 (mice, oral)
    149 (mice, intravenous)
    50 (dogs, oral)

    References:

    1. Kleemann A. Pharmaceutical Substances. - 2000. - pp. 1105
    2. Yalkowsky S.H., Yan H. Handbook of aqueous solubility data. - CRC Press, 2003. - pp. 267
    3. Полюдек-Фабини Р., Бейрих Т. Органический анализ. - Л.: Химия, 1981. - pp. 305-306
    4. Рубцов М.В., Байчиков А.Г. Синтетические химико-фармацевтические препараты. - М., 1971. - pp. 182-184
    5. Справочник химика. - Т.6. - Л..: Химия, 1967. - pp. 874-875
    6. Токсикологический вестник. - 2000. - №6. - pp. 46-47
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      © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru