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Properties of substance:

salicylamide

Physical appearance:

white crystals

Empirical formula (Hill's system for organic substances):

C7H7NO2

Structural formula as text:

HOC6H4CONH2

Molar/atomic mass: 137.14

Melting point (°C):

141

Solubility (g/100 g of solvent):

water: 0.1454 (15°C) [Ref.]
water: 0.21 (20°C) [Ref.]
water: 0.29 (30°C) [Ref.]
water: 0.73 (50°C) [Ref.]
1,4-dioxane: 24.8 (25°C) [Ref.]
diethyl ether: soluble [Ref.]
chloroform: sparingly soluble [Ref.]
ethanol: soluble [Ref.]

    LD50 (mg/kg):

    980 (rats, oral)
    300 (mice, oral)
    313 (mice, intravenous)

    References:

    1. Jouyban A. Handbook of solubility data for pharmaceutacals. – CRC Press, 2010. - pp. 72
    2. Kleemann A. Pharmaceutical Substances. - 2000. - pp. 1851-1852
    3. Seidell A. Solubilities of organic compounds. - 3ed., vol.2. - New York: D. Van Nostrand Company, 1941. - pp. 541
    4. Yalkowsky S.H., Yan H. Handbook of aqueous solubility data. - CRC Press, 2003. - pp. 386-387
    5. Беликов В.Г. Учебное пособие по фармацевтической химии. - М.: Медицина, 1979. - pp. 178
    6. Халецкий А.М. Фармацевтическая химия. - Л.: Медицина, 1966. - pp. 171-172
    7. Химический энциклопедический словарь. - Под ред. Кнунянц И.Л. - М.: Советсткая энциклопедия, 1983. - pp. 514
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      © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru